I've had x-notifier on Chrome for a long time on my Mac and two Windows machines (Win 7 and now Win 8). I have personal domain GMail, regular GMail, Yahoo and Hotmail (now called Outlook) accounts.
First, if you have Chrome syncing with your Gmail account, then it saves all your add-ons, etc to Google servers, so...One could export accounts from X-Notifier, and uninstall X-Notifier, and uninstall Chrome... and reinstall both. A problem with importing your X-Notifier accounts may be that you could import the problem back as well, perhaps.
Second, which is probably not your problem, is that the webmail providers, particularly Outlook, Hotmail, Live.com, are cracking down on the frequency of mail checking and will stop responding if too frequent. I think they mention 15 minutes, but may give a little 'grace' on that.
The Chrome setup seems more temperamental to me than Mozilla products (Firefox, Thunderbird, Sea Monkey).
Guessing
First, if you have Chrome syncing with your Gmail account, then it saves all your add-ons, etc to Google servers, so...One could export accounts from X-Notifier, and uninstall X-Notifier, and uninstall Chrome... and reinstall both.
A problem with importing your X-Notifier accounts may be that you could import the problem back as well, perhaps.
Second, which is probably not your problem, is that the webmail providers, particularly Outlook, Hotmail, Live.com, are cracking down on the frequency of mail checking and will stop responding if too frequent. I think they mention 15 minutes, but may give a little 'grace' on that.
The Chrome setup seems more temperamental to me than Mozilla products (Firefox, Thunderbird, Sea Monkey).